吕小妹教授 课题组
吕小妹，博士，江南大学食品学院研究员，博士生导师。主要从事食品合成生物学及食品酶学方向研究，专注于食品功能因子的绿色制备，国家优秀青年基金（海外）获得者、江苏省双创博士。发表SCI论文30余篇，主持国家自然科学基金青年项目、国家重点专项子课题、江苏省自然科学基金、江苏省双创博士项目等国家级、省部级课题7项，在健康食品绿色制造领域与多家企业开展合作。
邮箱：xmlyu@jiangnan.edu.cn
教育背景
2010.09-2015.06.硕博连读，浙江大学
2006.09-2010.06.本科，中国矿业大学
研究工作经历
2022.06-至今，研究员，江南大学食品学院
2019.10-2022.05，副研究员，江南大学食品学院
2015.10-2019.09，博士后，新加坡南洋理工大学
研究方向
食品功能配料的绿色生物制造
国家自然科学基金青年项目（22108097），2022-2024.
绿色生物制造重点专项子课题（2021YFC2100702），2021-2024.
江苏省青年基金（BK20200616），2020-2023.
江苏省双创博士(1026010241203190)，2020-2022
中国博士后科学基金（2020M671339），2020-2022
基本科研计划青年基金（JUSRP12008），2019-2021
企业技术服务，特膳食品创新设计与产品开发，2021-2024
1. Yan Lyu, Cheng Yang, Xiaomei Lyu,* and Kanyi Pu*，Active Delivery of CRISPR System Using Targetable or Controllable Nanocarriers, Small, 2021, 17, 2005222.
2. Lu Wang, Jiali Gu, Yinghui Feng, Mingming Wang, Yanjun Tong, Yingjie Liu, Xiaomei Lyu* and Ruijin Yang*, Enhancement of the Isomerization Activity and Thermostability of Cellobiose 2‑Epimerase from Caldicellulosiruptor saccharolyticus by Exchange of a Flexible Loop, Journal of Agriculture and Food Chemistry, 2021, 69, 1907−1915.
3. Yinghui Feng, Xiao Hua, Qiuyun Shen, Melissa Matthews, Yuzhu Zhang, Andrew J. Fisher, Xiaomei Lyu*, Ruijin Yang*, Insight into the potential factors influencing the catalytic direction in cellobiose 2-epimerase by crystallization and mutagenesis, Acta Crystallographica Section D-Structural Biology, 2020, D76, 1104-1113.
4. Xiaomei Lyu, Jaslyn Lee, Wei Ning Chen*, Potential natural food preservatives and their sustainable production in yeast: terpenoids and polyphenols, Journal of Agricultural and Food Chemistry, 2019,67,4397-4417.
5. Xiaomei Lyu, Guili Zhao, Kuan Rei Ng, Rita Mark, and Wei Ning Chen*, Metabolic Engineering of Saccharomyces cerevisiae for De Novo Production of Kaempferol, Journal of Agricultural and Food Chemistry, 2019,67,5596-5606.
6. Guili Zhao#, Xiaomei Lyu#, Jaslyn Lee, Xi Cui, Wei-Ning Chen*, Biodegradable and transparent cellulose film prepared eco-friendly from durian rind for packaging application, Food Packaging and Shelf Life, 2019,21, 100345.
7. Xiaomei Lyu, Kuan Rei Ng, Jie Lin Lee, Rita Mark, Wei Ning Chen*, Enhancement of Naringenin Biosynthesis from Tyrosine by Metabolic Engineering of Saccharomyces cerevisiae，Journal of Agriculture and Food Chemistry, 2017, 65,6638-6646.
8. Xiaomei Lv, Fan Wang, Pingping Zhou, Lidan Ye, Wenping Xie, Haoming Xu, Hongwei Yu*, Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae, Nature Communications，2016,7:12851
9. Xiaomei Lv, Jiali Gu, Fan Wang, Wenping Xie, Min Liu, Lidan Ye, Hongwei Yu*, Combinatorial Pathway Optimization in Escherichia coli by Directed Co-Evolution of Rate-Limiting Enzymes and Modular Pathway Engineering, Biotechnology and Bioengineering,2016, 113(12), 2661-2669.
10. Xiaomei Lv, Hongwei Yu* Significantly enhanced production of isoprene by ordered coexpression of genes dxs, dxr and idi in E. coli. Applied Microbiology and Biotechnology. 2013, 97:2357-2365.